Histology Atlas Curriculum

Skin / Integumentary System

Skin covers the external surface of our body and consists of the epidermis and the dermis. Together with epidermal derivatives (e.g. hair, sweat glands, sebaceous glands, and nails) it constitutes our integumentary system. The mammary gland is also a derivative of the epidermis.

Learning outcomes

You should be able to recognize the following structural components of thick and thin skin (where applicable) and know their functional significances:

  • Epidermis, stratum basale (germinativum), stratum spinosum, stratum granulosum, keratohyalin granules, stratum lucidum, stratum corneum.
  • Keratinocyte, melanocyte, melanin granule, Langerhans’ (antigen-presenting) cell and Merkel cell.
  • Epidermal peg.
  • Dermis – dermal papilla, papillary layer, reticular layer.
  • Hypodermis.
  • Meissner’s corpuscle and Pacinian corpuscle.
  • Eccrine sweat gland – duct portion, secretory portion, myoepithelial cell.
  • Apocrine sweat gland.
  • Sebaceous gland – basal cell, secretory acinus.
  • Hair – hair follicle, hair root (bulb), inner root sheath, outer root sheath, arrector pili muscle.
  • Nail – nail matrix, nail root.

Learning Modules

Sebaceous gland

Meissner’s corpuscle

Pacinian corpuscle


Apocrine sweat gland

Eccrine sweat gland



Thin skin

Thick skin

Interactive Histology Atlas + Descriptive Videos and Quizzes Special Offer

Sign up for 12 months access to the Interactive Histology Atlas (including Virtual Microscopy) for only $19.99 USD and get a Subscription to the Histology Videos for FREE.